COVID-19 and Marfan/VEDS/LDS: Your Questions Answered
26:33-29:48
Hal, do you want to take the other cardiovascular items listed here on the list?
Dietz先生、このリストにある心血管疾患について説明をお願いします。
Sure, one thing I would mention to add on to what Enid has said is that many people that have a pectus deformities, for example, that appears significant from a cosmetic standpoint, it looks fairly obvious and even striking to the family, many of those people do not have a significant impairment of lung capacity so just because a pectus looks abnormal does not infer that it's having a deleterious effect on the function of the lungs.
Enid先生がおっしゃったことに追加します。胸骨の変形がみられる多くの方、例えば、外見上目立つとか、家族が見てもはっきりわかるといったような場合ですが、こうした方の多くは肺機能に大きな問題はありません。胸骨が異常だからといって肺機能に悪影響があるということではありません。
And, you know, even if you've had pulmonary function tests, you know, some people have mild abnormalities that would be considered abnormal but they're not necessarily sufficiently severe to cause an increased risk in this context.
肺機能試験の結果で軽度の異常が認められる方もいらっしゃるかもしれませんが、だからといって必ずしも重症化リスクが高くなるというわけではありません。
So, you know, don't simply assume that because someone in your family or you personally have pectus or scoliosis that it has reached this threshold of severity.
よって、家族やあなた自身が胸骨の異常や側弯症があるからといって、単純に重症化リスクがあるとは考えないでください。
Aneurysm as I mentioned in and of itself including ascending aortic aneurysm or aortic root aneurysm would not put someone in a high risk category. Sometimes as an aneurysm expands it, does cause, for example, the aortic valve to leak and if that leakage is severe and has gone on for a long time, that could bump you up to a high risk category but simply having enlarged and enlarged blood vessel would not put you in a high risk category for severe features of this infection.
動脈瘤についてですが、上行大動脈や大動脈基部にできたものを含め、それ自体では、高リスクとはなりません。動脈瘤が大きくなることで大動脈弁のリークが生じたり、リークが重度で長期に及ぶ場合には高リスクとなる可能性がありますが、単純に瘤が大きくなったとか血管が太くなったということだけでは、新型コロナウイルス感染症による重症化リスクは高くはなりません。
Mild regurgitation again if, if something has been casually mentioned at appointments, someone is not having symptoms, they're not being followed at an increased frequency and they're not taking any additional medications on that basis, that would not be sufficient to put someone enough into a high risk category.
軽度の弁逆流がある場合ですが、診察でさり気なく指摘されたとか、無症状である、頻繁に検査を受ける必要がない、弁逆流の治療で追加の薬を飲んでいない、といった場合には、高リスクとは考えられません。
The same is true for previous aortic surgery or an artificial heart valve. If you're, you know, sufficiently out from the surgery and that happened a while ago and you're fully healed, if your heart, mechanical heart valve is functioning well, if you have a bicuspid aortic valve and abnormally formed aortic valve that's functioning well, that's not going to increase your risk for problems with this infection.
過去に大動脈や人工弁の手術を受けた方も同様です。手術を受けたのが随分昔だとか、しばらく前に手術を受け完全に回復している、機械弁の動きに問題がない、大動脈弁が二尖弁あるいは形に異常はみられるが、動きに問題はない、といったことでは、高リスクとはなりません。
If you have any doubts about any of this, you should discuss this with your primary care physician, cardiologist or geneticist but in general none of these categories would automatically put you in in a high-risk group.
心配な場合はかかりつけ医や循環器内科医、遺伝専門医などに相談すればいいのですが、一般には、このような疾患があるからといって、無条件にハイリスクとなることはありません。
The Marfan Foundation did not participate in the translation of these materials and does not in any way endorse them. If you are interested in this topic, please refer to our website, Marfan.org, for materials approved by our Professional Advisory Board.
The Marfan Foundation は、当翻訳には関与しておらず、翻訳内容に関してはいかなる承認も行っておりません。このトピックに興味をお持ちの方は、Marfan.org にアクセスし、当協会の専門家から成る諮問委員会が承認した内容をご参照ください。
