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Aortic Imaging: Your Questions Answered 18:22-19:57 How does dissection look by MRI, so this is an example on the right, left side top you see this cartoon with blood flowing through it and you're acquiring this angiogram multiple times an…
Aortic Imaging: Your Questions Answered 15:38-18:21 How is it done on MRI, which is MRA, MRA is a form of MRI but it's just magnetic resonance angiography where you give contrast and you can basically image the aortic root like here and th…
Aortic Imaging: Your Questions Answered 14:15-15:35 One important point if you take anything from this presentation is, this is probably the most important point. A lot of times the scans are done without gating. What do I mean by that? So…
Exercise and Marfan, LDS, and VEDS: The Latest Research 1:07:14-1:08:58 There are questions about, you know, what about the youngest, the youngest children and physical activity and sports and recreation and things like that and I've learn…
Exercise and Marfan, LDS, and VEDS: The Latest Research 1:04:32-1:07:12 And then some ask about one doing isometric exercise and I've been doing it for years and, and so the person that does push-ups and sit-ups and things like that, you k…
Exercise and Marfan, LDS, and VEDS: The Latest Research 1:03:57-1:04:29 A lot of them have to do with, you know, what if I've had surgery, so I've had my valve replaced or I've had my aorta replaced in part or and what does that mean for e…
Exercise and Marfan, LDS, and VEDS: The Latest Research 1:02:21-1:03:47 Q:Is there anything, any particular blood pressure monitor that you'd recommend people use during exercise? 運動中に血圧を測定する場合、おすすめの方法はありますか? A:…
Exercise and Marfan, LDS, and VEDS: The Latest Research 1:00:53-1:15:14 Q: So beginning questions are about the studies that you presented early on, talking about the mice because people were putting those questions in while they were list…
Exercise and Marfan, LDS, and VEDS: The Latest Research 49:27--57:20 So again, I think it's a great time now to study this in a prospective manner and gather information that can help prove this sort of information, is not only effective a…
Exercise and Marfan, LDS, and VEDS: The Latest Research 48:09-49:27 I'll end my discussion with just one slide from the 2022 ACC/AHA guidelines on the diagnosis of management of aortic disease, which was published this last week and for th…
Exercise and Marfan, LDS, and VEDS: The Latest Research 46:08-48:06 Now we're going to move on to the last part of our discussion before we open up the questions and this is a topic that's very unique and something that we're all very inte…
Exercise and Marfan, LDS, and VEDS: The Latest Research 34:46-46:06 Great, yes, so the first study I'd like to discuss is a pilot study from the Netherlands, again involving children ages 6 to 18 years old, primarily with the diagnosis of …
Exercise and Marfan, LDS, and VEDS: The Latest Research 27:26-34:46 OK, Siddharth, that was outstanding, very, very informative and to summarize the animal model studies of genetically programmed Marfan-like mice, aorta's benefit from, fro…
Exercise and Marfan, LDS, and VEDS: The Latest Research 26:05-27:22 And then after they completed the protocol we would survey the individuals about their experience. Half of them said they were more confident in their ability to safely co…
Exercise and Marfan, LDS, and VEDS: The Latest Research 25:22-26:02 We, we also looked at the aortic dissection subgroup. I mentioned that was a minority of patients but we wanted to make sure that was safe and effective for them. We did n…
Exercise and Marfan, LDS, and VEDS: The Latest Research 17:48-25:19 So our group has for the last two years studied the safety of exercise for our patients who come to clinic with thoracic aortic disease of all types and we started to do t…
Exercise and Marfan, LDS, and VEDS: The Latest Research 15:15-17:26 Thank you so much, Alan. That was for that excellent introduction. As, as we mentioned there are, there's some growing body of evidence that exercise is actually not only …
Exercise and Marfan, LDS, and VEDS: The Latest Research 13:45-15:14 Finally moving on to the guidelines in competition again intense activities for high schools, college and professional athletes competitive sports when you have an underly…
Exercise and Marfan, LDS, and VEDS: The Latest Research 12:16-13:44 You can kind of get a sense about the blood pressure and heart response to exercise depending upon the level of exercise. The metabolic equivalent of task or MET is one wa…
Exercise and Marfan, LDS, and VEDS: The Latest Research 11:01-12:04 Here's a schematic showing somebody who's doing a jog and you can see the systolic blood pressure, the top number, so at rest is constant. When you have onset of this jog …
Exercise and Marfan, LDS, and VEDS: The Latest Research 9:07-11:00 And those may differ again depending on what condition one has. Imagine somebody with significant eye features versus somebody with skeletal features, so exercise activity …
Exercise and Marfan, LDS, and VEDS: The Latest Research 8:16-9:06 So here are some of the questions that come up commonly about and, and what I think the simple answer is to say is we don't really have great answers for all these things. I…
Exercise and Marfan, LDS, and VEDS: The Latest Research 6:04-8:15 So as a bit of background this is a cartoon of a blood vessel wall like the aorta or another blood vessel and if, the thin lining layer is called the intima an endothelial c…
Exercise and Marfan, LDS, and VEDS: The Latest Research 3:45-6:02 This is kind of an overview of what we're going to share tonight and we'll try to get through. There's a lot of material, so we'll cover some of it more quickly and try to s…
Family Planning and Pregnancy: US and Europe Perspectives 1:05:26-1:07:51 Q: Do you have any women with Marfan who have also received a mechanical heart valve and are on blood thinners carrying a baby to term? You want to take that? Julie …
Family Planning and Pregnancy: US and Europe Perspectives 1:02:51-1:03:32 In summary most women with all connective tissue disorders have favorable outcomes in pregnancy, however, the diagnosis prior to pregnancy, proper surveillance, and …
Family Planning and Pregnancy: US and Europe Perspectives 1:01:15-1:02:49 Now another important thing is that postpartum you have multiple mom and baby so we're going to shift our attention to include the well-being of the child and their …
Family Planning and Pregnancy: US and Europe Perspectives 59:11-1:01:14 But one, one area of risk that has been focused upon is breastfeeding, so oxytocin and is a chemical released endogenously in each person that stimulates both labor an…
Family Planning and Pregnancy: US and Europe Perspectives 57:41-59:10 Overall the majority of aortic complications occur in the third trimester but it's also the postpartum period and that's something we haven't discussed at all yet, so wh…
Family Planning and Pregnancy: US and Europe Perspectives 56:04-57:40 Now cervical instability is another, another spiral manifestation that has an increased risk in Loeys-Dietz syndrome. This can be assessed with an x-ray of the cervical …