海外マルファン情報

米国マルファン症候群患者団体The Marfan Foundationからの情報を中心に、マルファン症候群や関連疾患についての海外情報を翻訳して発信します。

妊娠・出産

分娩について(2022_AHA/ACC大動脈疾患ガイドライン)

AHA/ACC Aortic Disease Guidelines: Delivery 0:00-3:43 Hello, my name is Mary Shepard from the University of Kentucky and it is my pleasure to be here today to talk with you about delivery and people who have aortic disease. ケンタッキー大…

妊娠について(2022_ACC大動脈疾患ガイドライン) 〜薬物治療〜

ACC Aortic Disease Guidelines: Pregnancy 5:53-6:34 To end some words about medication during pregnancy, so it is recommended that women take beta blockers throughout pregnancy and as contra-indicated this should be based on a shared decisi…

妊娠について(2022_ACC大動脈疾患ガイドライン) 〜心血管疾患カウンセリング〜

ACC Aortic Disease Guidelines: Pregnancy 4:02-5:52 Regarding cardiovascular counseling so as I mentioned this is important for, the for, the ladies, it, they should be informed that the risk for aortic dissection increases during pregnancy…

妊娠について(2022_ACC大動脈疾患ガイドライン) 〜遺伝カウンセリング〜

ACC Aortic Disease Guidelines: Pregnancy 0:00-4:02 Hello, my name is Julie De Backer. I am a cardiologist and clinical geneticist working at the Ghent University Hospital in Belgium and it is my pleasure to present to you today the topic o…

LDSガイドラインの改訂に向けて ~妊娠・出産~

LDS Guidelines: Then vs. Now 42:15-44:56 In terms of pregnancy I don't know that there's a heck of a lot of new changes either since 2024, or 2014, something to be aware of is that the angiotensin receptor blockers that Dr. Dietz was descr…

大動脈疾患の診断と管理に関するACC/AHAガイドライン2022 ~妊娠・出産について~

New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 40:54-46:17 Okay moving on to pregnancy. As Maya commented earlier that the emphasis on shared decision making and the importance of counseling, genetic counselin…

機械弁でも出産は可能か?

Family Planning and Pregnancy: US and Europe Perspectives 1:05:26-1:07:51 Q: Do you have any women with Marfan who have also received a mechanical heart valve and are on blood thinners carrying a baby to term? You want to take that? Julie …

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~結合組織疾患女性の妊娠・出産についてのまとめ~

Family Planning and Pregnancy: US and Europe Perspectives 1:02:51-1:03:32 In summary most women with all connective tissue disorders have favorable outcomes in pregnancy, however, the diagnosis prior to pregnancy, proper surveillance, and …

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~新生児の遺伝子検査~

Family Planning and Pregnancy: US and Europe Perspectives 1:01:15-1:02:49 Now another important thing is that postpartum you have multiple mom and baby so we're going to shift our attention to include the well-being of the child and their …

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~産後の授乳による大動脈解離リスク~

Family Planning and Pregnancy: US and Europe Perspectives 59:11-1:01:14 But one, one area of risk that has been focused upon is breastfeeding, so oxytocin and is a chemical released endogenously in each person that stimulates both labor an…

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~産後の画像検査~

Family Planning and Pregnancy: US and Europe Perspectives 57:41-59:10 Overall the majority of aortic complications occur in the third trimester but it's also the postpartum period and that's something we haven't discussed at all yet, so wh…

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~影響のある脊椎所見~

Family Planning and Pregnancy: US and Europe Perspectives 56:04-57:40 Now cervical instability is another, another spiral manifestation that has an increased risk in Loeys-Dietz syndrome. This can be assessed with an x-ray of the cervical …

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~硬膜拡張~

Family Planning and Pregnancy: US and Europe Perspectives 54:59-56:03 The spinal anatomy, which differs based on the genetic aortopathy that a person might have, can impact the anesthetic choice and these are a few examples: dural ectasia …

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~硬膜外麻酔と脊椎麻酔~

53:49-54:58 I wanted to just try to illustrate and, and simplify what we're talking about between these different types of anesthesia, so general anesthesia would generally require intubation and mechanical ventilation but with regional an…

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~分娩方法~

Family Planning and Pregnancy: US and Europe Perspectives 51:40-53:48 As introduced my name is Mary Shepard and I'm happy to be here to talk with you about delivery and postpartum care. I try to build this chart as a nice summary basically…

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~妊娠中管理のまとめ~

Family Planning and Pregnancy: US and Europe Perspectives 50:03-50:59 So I came to the to my final recommendations and as we have seen that pregnancy in patients with aortic disease should be managed by a multidisciplinary team and an expe…

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~ロイス・ディーツ症候群患者の場合~

49:01-50:02 So to conclude I would also make some, some discuss some aspects of pregnancy in patients with Loeys-Dietz syndrome although the data is much scarcer in this group and of course we know that the risk of aortic dissection during…

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~妊娠中の心血管手術のタイミングに関するメタアナリシス~

Family Planning and Pregnancy: US and Europe Perspectives 47:35-49:00 Of course, the question of the timing has been evaluated a little bit in more detail in this recently published meta-analysis and in this analysis they analyzed 386 pati…

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~妊娠中の心血管手術~

Family Planning and Pregnancy: US and Europe Perspectives 44:57-47:34 So I will continue with the final part of my presentation and discuss surgery during pregnancy and of course this is something we want to avoid but unfortunately still i…

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~妊娠中の心エコー・MRI・CT検査~

Family Planning and Pregnancy: US and Europe Perspectives 43:50-44:56 So all our patients with aortic disease should be seen on a regular basis throughout the pregnancy for evaluating the aortic root and echocardiography is the preferred d…

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~現行のガイドラインによる治療の転帰~

Family Planning and Pregnancy: US and Europe Perspectives 42:24-43:49 So does it pay off? Well, there are a few studies who actually evaluated the safety and the course of pregnancy in patients who are treated according to the current guid…

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~妊娠中の服薬~

41:21-42:23 So one of the previous speaker already discussed the use of the prophetic use of beta blocks in pregnancy. Well, some studies actually observed a reduced rate of progression of aortic dilatation, so according to the European gu…

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~妊娠中の画像検査~

Family Planning and Pregnancy: US and Europe Perspectives 39:56-41:20 So patients with aortic pathology should be overseen in specialized centers and supervised by both cardiologists and obstetricians who are actually aware of the potentia…

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~妊娠中の血行動態変化~

Family Planning and Pregnancy: US and Europe Perspectives 38:42-39:55 So there is an increased risk for aortic dissection in pregnancy, which is the result of both hemodynamic, hormonal but also from thromboembolic changes and actually pre…

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~医療チーム~

Family Planning and Pregnancy: US and Europe Perspectives 37:12-38:41 I will continue this webinar with the next topic, "the follow-up during pregnancy," so in the coming minutes I will discuss when we should see our patients and who actua…

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~循環器科のまとめ~

Family Planning and Pregnancy: US and Europe Perspectives 34:58-36:47 And then to end this presentation I just want to mention that every woman wanting to become pregnant should have a cardiac ultrasound done prior to pregnancy to look at …

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~前向き研究のデータからわかること~

Family Planning and Pregnancy: US and Europe Perspectives 34:13-34:57 So very briefly some prospective data and I'm going to skip this slide because I know that Martijn is going to address this one but I just want to mention with you that …

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~大動脈基部置換手術後のリスク~

Family Planning and Pregnancy: US and Europe Perspectives 32:58-34:12 So even after aortic root replacement because if you recommend replacement before pregnancy you should be aware that you are still not in an absolutely safe zone, so the…

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~予防的大動脈基部手術の基準値~

Family Planning and Pregnancy: US and Europe Perspectives 29:49-32:57 So how can we reduce the risk? As I mentioned knowing the diagnosis is really, really paramount. Pre-pregnancy counseling as Melissa has nicely explained. Follow-up duri…

妊娠・出産について(アメリカ・ヨーロッパの専門医の視点から) ~リスク推定~

Family Planning and Pregnancy: US and Europe Perspectives 28:52-29:49 So how can this risk be estimated? We use risk estimations and this is the most widely used risk estimation. The, WHO risk estimation where you have categories going fro…