Aortic Imaging: Your Questions Answered 18:22-19:57 How does dissection look by MRI, so this is an example on the right, left side top you see this cartoon with blood flowing through it and you're acquiring this angiogram multiple times an…

Aortic Imaging: Your Questions Answered 15:38-18:21 How is it done on MRI, which is MRA, MRA is a form of MRI but it's just magnetic resonance angiography where you give contrast and you can basically image the aortic root like here and th…

Aortic Imaging: Your Questions Answered 14:15-15:35 One important point if you take anything from this presentation is, this is probably the most important point. A lot of times the scans are done without gating. What do I mean by that? So…

Exercise and Marfan, LDS, and VEDS: The Latest Research 49:27--57:20 So again, I think it's a great time now to study this in a prospective manner and gather information that can help prove this sort of information, is not only effective a…

Exercise and Marfan, LDS, and VEDS: The Latest Research 46:08-48:06 Now we're going to move on to the last part of our discussion before we open up the questions and this is a topic that's very unique and something that we're all very inte…

Exercise and Marfan, LDS, and VEDS: The Latest Research 27:26-34:46 OK, Siddharth, that was outstanding, very, very informative and to summarize the animal model studies of genetically programmed Marfan-like mice, aorta's benefit from, fro…

Exercise and Marfan, LDS, and VEDS: The Latest Research 25:22-26:02 We, we also looked at the aortic dissection subgroup. I mentioned that was a minority of patients but we wanted to make sure that was safe and effective for them. We did n…

Exercise and Marfan, LDS, and VEDS: The Latest Research 17:48-25:19 So our group has for the last two years studied the safety of exercise for our patients who come to clinic with thoracic aortic disease of all types and we started to do t…

Exercise and Marfan, LDS, and VEDS: The Latest Research 6:04-8:15 So as a bit of background this is a cartoon of a blood vessel wall like the aorta or another blood vessel and if, the thin lining layer is called the intima an endothelial c…

Family Planning and Pregnancy: US and Europe Perspectives 59:11-1:01:14 But one, one area of risk that has been focused upon is breastfeeding, so oxytocin and is a chemical released endogenously in each person that stimulates both labor an…

Family Planning and Pregnancy: US and Europe Perspectives 57:41-59:10 Overall the majority of aortic complications occur in the third trimester but it's also the postpartum period and that's something we haven't discussed at all yet, so wh…

Family Planning and Pregnancy: US and Europe Perspectives 50:03-50:59 So I came to the to my final recommendations and as we have seen that pregnancy in patients with aortic disease should be managed by a multidisciplinary team and an expe…

49:01-50:02 So to conclude I would also make some, some discuss some aspects of pregnancy in patients with Loeys-Dietz syndrome although the data is much scarcer in this group and of course we know that the risk of aortic dissection during…

Family Planning and Pregnancy: US and Europe Perspectives 44:57-47:34 So I will continue with the final part of my presentation and discuss surgery during pregnancy and of course this is something we want to avoid but unfortunately still i…

Family Planning and Pregnancy: US and Europe Perspectives 43:50-44:56 So all our patients with aortic disease should be seen on a regular basis throughout the pregnancy for evaluating the aortic root and echocardiography is the preferred d…

Family Planning and Pregnancy: US and Europe Perspectives 42:24-43:49 So does it pay off? Well, there are a few studies who actually evaluated the safety and the course of pregnancy in patients who are treated according to the current guid…

41:21-42:23 So one of the previous speaker already discussed the use of the prophetic use of beta blocks in pregnancy. Well, some studies actually observed a reduced rate of progression of aortic dilatation, so according to the European gu…

Family Planning and Pregnancy: US and Europe Perspectives 39:56-41:20 So patients with aortic pathology should be overseen in specialized centers and supervised by both cardiologists and obstetricians who are actually aware of the potentia…

Family Planning and Pregnancy: US and Europe Perspectives 38:42-39:55 So there is an increased risk for aortic dissection in pregnancy, which is the result of both hemodynamic, hormonal but also from thromboembolic changes and actually pre…

Family Planning and Pregnancy: US and Europe Perspectives 37:12-38:41 I will continue this webinar with the next topic, "the follow-up during pregnancy," so in the coming minutes I will discuss when we should see our patients and who actua…

Family Planning and Pregnancy: US and Europe Perspectives 34:58-36:47 And then to end this presentation I just want to mention that every woman wanting to become pregnant should have a cardiac ultrasound done prior to pregnancy to look at …

Family Planning and Pregnancy: US and Europe Perspectives 34:13-34:57 So very briefly some prospective data and I'm going to skip this slide because I know that Martijn is going to address this one but I just want to mention with you that …

Family Planning and Pregnancy: US and Europe Perspectives 32:58-34:12 So even after aortic root replacement because if you recommend replacement before pregnancy you should be aware that you are still not in an absolutely safe zone, so the…

Family Planning and Pregnancy: US and Europe Perspectives 29:49-32:57 So how can we reduce the risk? As I mentioned knowing the diagnosis is really, really paramount. Pre-pregnancy counseling as Melissa has nicely explained. Follow-up duri…

Family Planning and Pregnancy: US and Europe Perspectives 28:52-29:49 So how can this risk be estimated? We use risk estimations and this is the most widely used risk estimation. The, WHO risk estimation where you have categories going fro…

Family Planning and Pregnancy: US and Europe Perspectives 26:21-28:53 So risk factors in the setting of, of, of Marfan disease and related heritable thoracic aortic diseases diagnosis of the aortopathy is really crucial. Most women in seri…

Family Planning and Pregnancy: US and Europe Perspectives 22:52-26:21 I will be addressing firstly what is the risk that we are talking about, how can we estimate the risk, how can we reduce the risk and I'll be addressing prophylactic sur…

Aortic Disease Research (9/19/22) 34:55-38:43 So bicuspid aortic valve is a very common inherent disorder of the aortic valve and a certain percentage of patients 10 to 35 percent also have an abnormal, abnormal aorta. I think it's estimat…

Aortic Disease Research (9/19/22) 20:42-23:20 So, this was a very interesting analysis. Sherene Shalhub and others led a large group of patients to try to understand from patients and families, what, what are the research priorities that y…

Aortic Imaging: Your Questions Answered 13:28-14:14 The other image I want to share here is how does a dissection look on CT. So this is basically what we call a snake view of the aorta, whole of the aorta. On the top is the root as you co…