海外マルファン情報

米国マルファン症候群患者団体The Marfan Foundationからの情報を中心に、マルファン症候群や関連疾患についての海外情報を翻訳して発信します。

循環器

Tromsø Aorta 2024 からの報告 ~大動脈解離後の運動に関する研究~

Tromsø Aorta 2024 Recap with Dr. Kim Eagle 22:58-26:42 You know, there's been a very big space that we need to fill which is what I call survivorship after aortic dissection or thrivership if we talk about not just surviving but thriving w…

Tromsø Aorta 2024 からの報告 ~vEDSにおける薬物管理~

Tromsø Aorta 2024 Recap with Dr. Kim Eagle 13:03-15:02 One of the really interesting talks that we heard in Tromsø was a trial that is looking at the management of patients with vascular EDS. This was a small study, I think less than 60 pa…

Tromsø Aorta 2024 からの報告 〜医療体制〜

Tromsø Aorta 2024 Recap with Dr. Kim Eagle 11:18-12:58 One of the things that's very clear from presentations that we heard at Tromsø is that regions that have organized themselves to try to make diagnosis and rapid management of aortic di…

Tromsø Aorta 2024 からの報告 〜大動脈解離〜

Tromsø Aorta 2024 Recap with Dr. Kim Eagle 8:14-11:13 There was a lot of discussion about where we're at with diagnosis of this dangerous condition called aortic dissection when the aorta tears. The hallmark feature of an aortic dissection…

小児における大動脈弓部の問題について

Applying AHA's 2024 Scientific Statement: Navigating Diagnosis & Management of Pediatric Aortopathy 58:51-1:01:05 Q: How often do you see complications in the aortic arch? 大動脈弓部の合併症はどのくらいの頻度でみられますか? A: I can start…

ARBとβブロッカーの併用について

Applying AHA's 2024 Scientific Statement: Navigating Diagnosis & Management of Pediatric Aortopathy 52:50-54:51 Q: In the statement, you mentioned dual therapy if tolerated. What does "if tolerated" mean? What are indicators to change medi…

アテノロールとプロプラノロールについて

Applying AHA's 2024 Scientific Statement: Navigating Diagnosis & Management of Pediatric Aortopathy 51:52-52:44 Q: Is atenolol the preferred treatment for children four and under? 4歳以下の小児については、アテノロールのほうが好ましいですか…

ステートメント付録の画像検査の表について

Applying AHA's 2024 Scientific Statement: Navigating Diagnosis & Management of Pediatric Aortopathy 48:09-51:48 Q: Does the statement include specifics on baseline imaging when newly diagnosed? ステートメントには、診断が付いてから最初に行…

小児の大動脈解離発症リスクについて

Applying AHA's 2024 Scientific Statement: Navigating Diagnosis & Management of Pediatric Aortopathy 44:00-48:06 Q: For the shared decision making, it would be helpful to know, uh, to better, to know, excuse me, to know better estimates of …

ロサルタンの服用開始時期について

Applying AHA's 2024 Scientific Statement: Navigating Diagnosis & Management of Pediatric Aortopathy 43:21-43:53 Q: What age should Losartan be started or is it just based on z-score? ロサルタンは何歳から飲み始めればいいでしょうか?それとも…

小児における大動脈疾患の診断と管理に関するステートメント 〜まとめ〜

Applying AHA's 2024 Scientific Statement: Navigating Diagnosis & Management of Pediatric Aortopathy 20:59-24:18 So in summary, this statement is the first attempt at really putting everything about management of pediatric aortopathy in one…

小児における大動脈疾患の診断と管理に関するステートメント 〜付録〜

Applying AHA's 2024 Scientific Statement: Navigating Diagnosis & Management of Pediatric Aortopathy 18:30-20:57 And these are the different sections that are included in the paper. So you might imagine that the sections on Marfan syndrome,…

小児における大動脈疾患の診断と管理に関するステートメント 〜予防的外科手術〜

Applying AHA's 2024 Scientific Statement: Navigating Diagnosis & Management of Pediatric Aortopathy 17:38-18:26 And then there's a table on surgery, when to do surgery. Again, the lighter blue is standard risk. If there are high-risk featu…

小児における大動脈疾患の診断と管理に関するステートメント 〜運動〜

Applying AHA's 2024 Scientific Statement: Navigating Diagnosis & Management of Pediatric Aortopathy 15:05-17:34 Now this is the table, as Dr. Morris mentioned earlier, we wanted to approach exercise in a little bit different way than it ha…

小児における大動脈疾患の診断と管理に関するステートメント 〜薬物治療〜

Applying AHA's 2024 Scientific Statement: Navigating Diagnosis & Management of Pediatric Aortopathy 13:02-15:02 And so for all of these slides, what we do is we basically provide a framework for how to manage patients, and this framework n…

小児における大動脈疾患の診断と管理に関するステートメント 〜画像検査の表の見方〜

Applying AHA's 2024 Scientific Statement: Navigating Diagnosis & Management of Pediatric Aortopathy 9:30-11:30 So just to give some highlights, this is big picture taking a step back of the Imaging table here. We'll do a zoom up, but the I…

小児における大動脈疾患の診断と管理に関するステートメント 〜トピックについて〜

Applying AHA's 2024 Scientific Statement: Navigating Diagnosis & Management of Pediatric Aortopathy 8:20-9:29 So this is the main outline of the statement. The first part of the statement is evaluation of the child with suspected aortopath…

小児における大動脈疾患の診断と管理に関するステートメント 〜ステートメントについて〜

Applying AHA's 2024 Scientific Statement: Navigating Diagnosis & Management of Pediatric Aortopathy 5:03-8:18 So first of all, why did we put this together? Well, we know that aortopathy, which is a word that encompasses various conditions…

血圧・アルコールと心房細動の関係について

Aging with a Connective Tissue Condition 49:41-50:09 Q: Can lifestyle changes reduce the risk of blood clots and atrial fibrillation? 生活習慣の改善によって、血栓や心房細動のリスクを下げることはできますか? A: Yes, it's a little hard to pr…

血管の石灰化について

Aging with a Connective Tissue Condition 49:10-49:38 Q: What are the options when the heart has calcified? 心臓の石灰化に対しては、どのような治療選択肢がありますか? A: Well, so calcification of blood vessels is an expected change with agi…

VEDSにおけるカテーテルアブレーションについて

Aging with a Connective Tissue Condition 48:24-49:08 Q: Are cardiac ablation safe for individuals with VEDS? カテーテルアブレーションはVEDS(血管型エーラス・ダンロス症候群)の患者でも安全にできますか? A: Well, that's a good question. That…

心筋梗塞と大動脈解離の痛みの違いについて

Aging with a Connective Tissue Condition 44:03-45:11 Q: Could you please elaborate on how a heart attack and a dissection might feel different for someone? 心筋梗塞の痛みと大動脈解離の痛みの感じ方に違いはあるのでしょうか?詳しい説明をお願…

結合組織疾患と加齢 〜結合組織疾患と心臓病およびがんの関連〜

Aging with a Connective Tissue Condition 20:10-25:11 Now let's talk just a little bit about Marfan syndrome and related conditions. Dr. Pyeritz wrote this editorial some years ago, how research does pay off and does lead to improvements in…

結合組織疾患と加齢 〜大動脈の変化〜

Aging with a Connective Tissue Condition 17:07-18:02 Let's switch to the aorta because many of you have problems with your aorta. This is a normal thoracic aorta with a lot of elastic tissue, which appears yellow here, and nice, normal pul…

結合組織疾患と加齢 〜弁膜症〜

Aging with a Connective Tissue Condition 14:28-17:06 Now talking about heart valve aging, one of the most common heart valve problems in the world that affects not only people with Marfan syndrome and related conditions but also the genera…

結合組織疾患と加齢 〜心房細動(不整脈)〜

Aging with a Connective Tissue Condition 12:39-14:27 We’re going to talk next about atrial fibrillation, which many of you have had where your nice, a cardiac rhythm, which is you can see down here, becomes disorganized because the upper c…

結合組織疾患と加齢 〜高血圧〜

Aging with a Connective Tissue Condition 11:42-12:38 Now, we’ll shift gears and talk about hypertension, which can harm you through eventually producing heart failure, eventually causing a stroke, and eventually wearing out your kidneys. S…

結合組織疾患と加齢 〜心臓発作(心筋梗塞)〜

Aging with a Connective Tissue Condition 8:56-11:41 Now let's take a minute and just look at the big factors in heart disease because we're going to experience these ourselves. So heart attack is a big cause of death, complications of high…

マルファン症候群における肺気腫・睡眠時無呼吸の研究 〜睡眠時無呼吸とDダイマーの関係〜

Investigation of Sleep Disorders and Lung Injury in Marfan Syndrome 28:43-32:45 And the last study that we did was that we wanted to know whether we could identify a blood biomarker that could select the patients with sleep apnea that had …

マルファン症候群における肺気腫・睡眠時無呼吸の研究 〜睡眠時無呼吸と大動脈拡張の関係〜

Investigation of Sleep Disorders and Lung Injury in Marfan Syndrome 19:37-28:42 And now I want to transition to sleep apnea which our group has done a lot of work on and many of you have contributed to the studies that we've conducted and …