Loeys Dietz Syndrome: Virtual Medical Symposium Series (11/8/18)
22:38-24:38
There are a number of gastrointestinal conditions that can be seen in Loeys-Dietz syndrome. One of the most common is a condition called eosinophils esophagitis, a form of inflammation of the tube going from the mouth to the stomach.
ロイス・ディーツ症候群で認められる胃腸障害はいくつかあります。最も多いのが、好酸球性食道炎で、口から胃までの食道で起きる炎症の一種です。
When young children have eosinophils esophagitis, they can show pretty nonspecific findings such as vomiting or abdominal pain. Some of these children just simply are not interested in eating and they show poor weight gain, but often it's hard to get a specific comment that their throat hurts or that it hurts to swallow, so the pediatrician needs to be sensitive to many possible clues that this type of inflammation may be present.
小児が好酸球性食道炎を発症した場合、嘔吐や腹痛などの一般的な症状がみられることがあります。「食欲がない」、「体重が増えない」と訴える小児もいます。ですが、「喉が痛い」、「飲み込む時に痛い」などの具体的な訴えがないことも多いので、小児科医はこの種の疾患が疑われる所見に注意を払う必要があります。
In older children and adults, it's often easier to get a specific history that they have trouble swallowing, that there's a sensation that food is getting stuck, or that there's chest pain.
年長の小児や成人の場合は、「飲み込みづらい」、「食べ物が詰まったような感じがする」、「胸が痛い」などの具体的な訴えがあることが多いです。
This condition eosinophils esophagitis, is often very effectively managed simply by finding the food that's triggering an allergic response, so again very important to have this evaluated by a gastroenterologist and perhaps by an allergist.
好酸球性食道炎に関しては、アレルギー反応を引き起こす食物を特定するだけで管理が非常に上手くいくことが多いので、胃腸科専門医やアレルギー専門医の診察を受けることがとても大切です。
In a smaller subset of people there can be a more severe inflammation called inflammatory bowel disease. This can be associated with diarrhea or with blood in the stool and this, this type of finding really should be evaluated very early if there's any sense of severe gastrointestinal problems. It's essential to see a gastroenterologist who can help manage the inflammation.
炎症性腸疾患と呼ばれる重篤な炎症が認められる方も一部いらっしゃいます。下痢や血便などの症状があります。激しい胃腸疾患がある場合には、すぐに病院を受診してください。対応できる胃腸科専門医に診てもらうことが重要です。
The Marfan Foundation did not participate in the translation of these materials and does not in any way endorse them. If you are interested in this topic, please refer to our website, Marfan.org, for materials approved by our Professional Advisory Board.
The Marfan Foundation は、当翻訳には関与しておらず、翻訳内容に関してはいかなる承認も行っておりません。このトピックに興味をお持ちの方は、Marfan.orgにアクセスし、当協会の専門家から成る諮問委員会が承認した内容をご参照ください。
