Exercise and Marfan, LDS, and VEDS: The Latest Research
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Q:
So beginning questions are about the studies that you presented early on, talking about the mice because people were putting those questions in while they were listening, so what was the average duration and frequency of exercise that contributed to reduction of dilatation in mice, Marfan mice?
セミナーの序盤で紹介されたマルファンマウスの研究に関する質問です。大動脈基部の拡張速度低下に効果があった運動期間と運動頻度の平均を教えてください。
A:
Right, so in, in the Marfan mice this was over five months, which is in mouse terms is a fairly long period of exercise considering that mice live only a couple years and, and the, the exercise was really a treadmill or a wheel in the cage and so the mice would be running on the wheel at different speeds adjusted to different levels of intensity but because, because of the, the nature of the trial it was simply they would record the, the amount of time that the mouse spent on the wheel but there was no enforcement of that, so most, most of the mice were uniformly active but they were free to approach the wheel at any time and so the net effect of this was a period of five months of activity versus no wheel in the cage and, and just regular kind of movement in the the cage.
マルファンマウスの平均運動期間は5ヶ月以上です。マウスの寿命がわずか2、3年であることを考慮すると、この期間は非常に長い期間といえます。運動の種類は、トレッドミル、つまりカゴの中に置かれた回るホイールを、様々な運動強度レベルに合わせて、異なる速度で走る運動です。この試験の性質から、ホイールを走った時間を単純に計測しただけであり、強制的に走らせたわけではありません。よって、大部分のマウスは一様に活動的であったものの、ホイールを走るかどうかについてはマウス次第であり、運動の実質的な効果については、5ヶ月間運動したマウスとホイールのないカゴの中でいつも通りに動いていたマウスとの比較になります。
The Marfan Foundation did not participate in the translation of these materials and does not in any way endorse them. If you are interested in this topic, please refer to our website, Marfan.org, for materials approved by our Professional Advisory Board.
The Marfan Foundation は、当翻訳には関与しておらず、翻訳内容に関してはいかなる承認も行っておりません。このトピックに興味をお持ちの方は、Marfan.org にアクセスし、当協会の専門家から成る諮問委員会が承認した内容をご参照ください。
