海外マルファン情報

米国マルファン症候群患者団体The Marfan Foundationからの情報を中心に、マルファン症候群や関連疾患についての海外情報を翻訳して発信します。

画像検査で大動脈の厚さはわかるか?


Aortic Imaging: Your Questions Answered

 

50:01-51:59

 

Q:
You know, I had a, we got a couple of questions in advance about looking at the thickness or thinness of the aortic wall, so can you talk about that a little bit like, are you looking at that with these images the thinning of the aortic tissue and do these different tests measure that as well?

 

大動脈の壁の厚さや薄さについての質問をいくつかいただいています。画像検査で大動脈の薄さは計測しているのでしょうか?とのことです。

 

A:
Yeah, so that's a very good question. We can see the wall of the aorta definitely on different techniques and we can, the measurement of the wall thickness is very difficult if you can think of how thin the wall is. What ends up happening is the spatial resolution in the sense that ability to differentiate between two points is less. It's so thin it becomes very tough to measure but what do we know is when there is an aneurysm formation the wall is thinning already and I think if everybody, if there are physicists on the call they recognize the wall stress increases, exactly opposite of the wall thickness, it's not direct, it's not a directive. As the radius increases wall stress increases but the wall thins this wall stress increases, so we know the wall stress goes up as the aneurysm formation happens in the wall thin but to answer their question I don't think there is a very reliable methodology of measuring the wall thickness yet you can measure it but I don't think it's as reproducible yet. Okay, thank you because you've got a couple of questions about that in advance. What we can measure though is the wall stress there are techniques which are being validated to measure the wall stress itself, which would be very good. 

 

大動脈の壁は様々な技術を使って調べることができますが、大動脈の壁の薄さを測るとなると非常に難しいと言わざるを得ません。なぜかというと、大動脈壁が薄くなると、二点を区別する能力である空間分解能が低下してしまい、厚さを測定することが難しくなるからです。動脈瘤ができると大動脈の壁は薄くなることはわかっていますので、検査で大動脈壁にかかる圧力が高くなっていれば、大動脈の壁が薄くなっていることを意味しています。質問の回答としては、大動脈の壁の厚さを直接的に測ることのできる、信頼のおける再現性の高い方法はない、ということになりますが、大動脈壁にかかる圧力を測定する方法は確立されており、それは非常に信頼性の高い方法だということです。

 

The Marfan Foundation did not participate in the translation of these materials and does not in any way endorse them. If you are interested in this topic, please refer to our website, Marfan.org, for materials approved by our Professional Advisory Board.

The Marfan Foundation は、当翻訳には関与しておらず、翻訳内容に関してはいかなる承認も行っておりません。このトピックに興味をお持ちの方は、Marfan.org にアクセスし、当協会の専門家から成る諮問委員会が承認した内容をご参照ください。