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Keeping Your Spine, Limbs, and Feet Healthy in Marfan and Related Conditions
24:49-25:53
So pain. Unfortunately as good as we are like, Dr. Sponseller said, we don't have a great understanding on exactly the true cause of pain because there are many symptoms that can present as pain and unfortunately no two patients presenting with pain have a similar presentation.
残念ながら痛みについては、先ほどSponseller先生からもあったように、原因は正確にわかっていません。というのは、多くの症状が痛みとして現れ、痛みを訴える患者さんで、同じ症状の方はいないからです。
Related to the musculoskeletal or the orthopedic standpoint, scoliosis or the curvature as mentioned to the spine is a major possibility and a major cause. TGF-beta and other cytokines are important chemicals that are floating around the bloodstream. They may be related to the causing pain. Dural ectasia is as mentioned and then the degenerative arthritis or the bone-on-bone contact that results from these deformities particularly in the lower extremity.
筋骨格系あるいは整形外科的な観点から考えると、側弯症が痛みの主な原因と考えられます。また、血中にある重要な化学物質であるTGF-βやその他のサイトカインもその可能性がありますし、先ほどあったような硬膜拡張も要因です。関節が変形することで、骨と骨とが接触する変形性関節症は、特に下肢の痛みの要因となります。
Again when you're walking 10,000 steps, when you're active or as active as you can be in your daily life working or even socially, eventually all things break down and lead to wear and tear, which can cause pain.
1万歩歩いたり、仕事や社会的活動などで忙しくしているうちに身体が消耗し、結果として痛みが出てくるのだと考られます。
The Marfan Foundation did not participate in the translation of these materials and does not in any way endorse them. If you are interested in this topic, please refer to our website, Marfan.org, for materials approved by our Professional Advisory Board.
The Marfan Foundation は、当翻訳には関与しておらず、翻訳内容に関してはいかなる承認も行っておりません。このトピックに興味をお持ちの方は、Marfan.org にアクセスし、当協会の専門家から成る諮問委員会が承認した内容をご参照ください。
