LDS Guidelines: Then vs. Now 10:33-16:15 So back 10 years ago we knew that Marfan syndrome related to alterations in the activity of a molecule called TGF beta. That's a mechanism by which cells talk to themselves or talk to each other and…
LDS Guidelines: Then vs. Now 7:54-10:15 So one of the big things that differentiated Loeys-Dietz syndrome from Marfan syndrome in the very beginning was this recognition, right? that aortic diameters could show dissections or tears at smal…
LDS Guidelines: Then vs. Now 6:30-7:47 So kind of a late breaking also research discovery that we wanted to bring forward is that there was a paper earlier this year that described a possible new Loeys-Dietz gene, so this is not clinically…
LDS Guidelines: Then vs. Now 4:23-6:27 So again, this is the, the primer that many specialists, most of them from Johns Hopkins, because back in the day we had the most experience with Loeys-Dietz, so our specialist came together to write …
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 1:05:49-1:07:41 Q:There's a lot of questions about PEARS surgery. Abe, are you comfortable talking about the PEARS? PEARSについての質問を多くいただいています。DeA…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 1:05:09-1:05:47 Q:What percentage of Marfan patients will experience in aortic dissection or require surgery? マルファン患者で大動脈解離を発症する人の割合、外科手…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 1:04:10-1:05:06 Q:Here's a question my daughter was diagnosed with Loeys-Dietz but dad and I were tested and don't have it. Should we get an echo to check the aor…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 1:02:52-1:04:10 Q:Abe, maybe you can answer this if you have, if you know what's typically done with celiac and splenic artery dilations at what size is typically…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 1:00:51-1:01:29 Q:When to start aortic, how old to start aortic screening relatives? 家系に結合組織疾患患者がいるのですが、その者の親族に対して大動脈の検査を行う…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 59:51-1:00:45 Q:One person asked the important question. Is there a recommended age cutoff for peripheral aneurysms when considering genetic testing? 末梢の動脈瘤…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 58:58-59:50 Q:Here's a question when my husband and children go to their cardiology appointments do they need an MR, CT as well as an echo? 夫と子供が循環器内科で…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 55:40-58:02 And then we've talked about multiple dis.., multiple disciplinary aor.., multi-disciplinary aortic teams multiple times tonight, sometimes called cent…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 54:38-55:36 Another section of the paper was talking about quality of life both in the importance of regular mild to moderate physical activity and if you're not …
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 53:22-54:33 And and then finally some patients will have an arch, aortic arch aneurysm and they may have symptoms that are attributed to the aneurysm. If, as long…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 51:56-53:18 And then finally and these were some of the biggest talking points that we added on to the, to the regulations for type A dissection. When there is de…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 50:55-51:51 And finally, the, there's class 2A recommendation when it comes to type A aortic dissections and this, this did come from a lot of discussion and that…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 49:22-50:51 Some of the reasons why this became a class one recommendation in, in terms of malperfusion, this is paper that came out of the University of Michigan…
納屋での重労働はお手のもの。自称「ウマ娘」のモーリーは、俵形をした80ポンド（約36キログラム）の干し草を放り投げていました。子供の頃から馬を乗りこなし、丈夫で健康に恵まれていた彼女。ところが、大学入学を数週間後に控えた2017年のこと。息切れと…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 46:22-49:18 For the class, I'm going to go through this fairly quickly. These are the class one recommendations for type A aortic dissections and I've included th…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 40:54-46:17 Okay moving on to pregnancy. As Maya commented earlier that the emphasis on shared decision making and the importance of counseling, genetic counselin…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 38:08-40:48 Moving on to vascular Ehlers-Danlos syndrome in, and in vEDS. In imaging the aorta and the branches is very important because it may identify arterial…
30:17-36:57 This, this slide just emphasizes a little bit of difference in management and Loeys-Dietz syndrome, so in Loeys-Dietz syndrome imaging because aneurysm disease is more widespread than in Marfan syndrome that baseline MR or CT a…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 27:36-30:06 Dr. DeAnda is going to walk us through surgical thresholds in Marfan syndrome aortic root enlargement. では、DeAnda先生からマルファン症候群の大動脈基…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 25:57-27:33 Okay, what's new in Marfan syndrome? Well, moving on to medical therapy. Those on the, on the webinar tonight with Marfan syndrome they're probably we…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 20:53-25:55 Dr. DeAnda is going to talk about some of the surgical thresholds. では、DeAnda先生から外科手術のしきい値についてお話いただきます。 Some of this has c…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 17:08-20:51 The recommendations are written like this, so I won't go over every single one but it emphasizes again in somebody, in a patient who has thoracic aort…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 14:07-17:03 So what we're going to do over the next half hour or so is we're going to review some of the topics that are encompassed in the new guidelines based o…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 10:57-14:08 So this is not a new concept but I think what's so important about the document is how all these various numbers and sizes and things that we talk abo…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 9:03-10:48 Maya Brown Zimmerman is going to talk to us about one of the most important aspects of the guidelines, the concept of shared decision making. では、ガ…
New ACC/AHA Aortic Disease Management Guidelines: What do they mean for you? 7:10-9:00 One of the most important parts of the guidelines is really a whole section on emphasizing how to measure the aorta. Everyone who sees individuals and, …
